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PHENOMIN-Institut Clinique de la Souris
Responsable : HERAULT • Responsable Tech. : SORG
Adresse : 1 rue Laurent Fries



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Presentation de la plate-forme

The Institut Clinique de la Souris (ICS), infrastructure of excellence in translational research and functional genomics provides scientists with a broad set of highly specialized services regarding mouse models for human pathologies, develops and shares relevant research and development program through the PHENOMIN project. Genetic researches are conducted and supported combining generation, validation and phenotyping analysis of mutant mice model (physiological, behavioral and anatomical analysis).

We can structure the services offered by platform

-Generation of new mouse models
-Genetic analysis
-Housing in ventilated cages
-Metabolism and nutrition
-Cardiovascular domain
-Respiratory domain
-Imaging (Ultrasound)
-Histopathology and embryology
-Cryopreservation of mouse lines (embryos)
-Cryopreservation of mouse lines (cperm or ovaries)
-Mutant lines shipped outside
-Training with diploma
-Continuing education program
-Certified animal experimentation program

Moyens et equipements

-Automation of cage washing process (Tunnel)
-Quantum FX (µCT)
-High resolution echography Vevo 2100
-Indirect calorimetry measurment
-System for Indirect gas calorimetry uses measurements of the animal’s oxygen consumption (VO2) and carbon dioxide production (VCO2) to estimate various metabolic parameters, including the respiratory exchange rate (RQ), energy expenditure (EE), substrate utilization (fat reserves vs. carbohydrate catabolism), and more.